In these cases of refractory epilepsy, long-term or lifelong antiepileptic drug therapy is often required. 这些顽固性癫痫患者常常需要长期或终身服用抗癫痫药物。
Focus on antiepileptic drug combination and drug toxicity 关注抗癫癎药的联合用药警惕药物中毒
Purpose: The use of alternate methods for antiepileptic drug delivery has been proposed as a putative strategy to enhance efficacy and tolerability of chronic pharmacotherapy. 抗惊厥的给药的选择性方式已经成为一种公认的提高其慢性药物疗法效能和耐受度的策略。
These altered circulatory markers from prolonged antiepileptic drug therapy may accelerate the atherosclerotic process. 这是由于长期抗癫痫治疗导致血液指标改变并加速动脉粥样硬化的过程。
Based on these data, intranasal phenobarbital administration seems to render a suitable alternate delivery route for this antiepileptic drug, which should be further evaluated. 基于这些数据,鼻内给予***也许能成为一种这种抗惊厥药物合适的选择性的给药途径,这还有待于进一步的研究。
FDA issued the warning based on data collected from the North American Antiepileptic Drug Pregnancy Registry. 美国食品及药物管理局发出警告基于数据收集了来自北美癫痫药物怀孕登记处。
Conclusions Sustained release tablets of magnesium valproate has well therapeutic effect, well dependence, it is an ideal antiepileptic drug. 结论丙戊酸镁缓释片具有较好的临床疗效和药物依从性,是较理想的抗癫痫药物。
Objective: To study the diagnosis, treatment and prognosis of antiepileptic drug hypersensitive syndrome ( DHSS). 目的:探讨小儿抗癫痫药物过敏反应综合征的诊断、治疗及预后。
Risks of cognitive side-effects with antiepileptic drugs can add to previous damage by surgery or radiotherapy, and therefore appropriate choice and dose of antiepileptic drug is crucial. 我们已经认识到抗癫痫药物的副反应风险可以加重从前的手术或放疗造成的损伤,因此恰当的选择抗癫痫药物及其剂量是极其重要的。
Intoxication with antiepileptic drugs, edema after generalized seizures, or a rapid change of antiepileptic drug levels have been proposed as possible mechanisms. 其机制可能为抗癫痫药物的毒性作用、全身发作之后引起的(脑)水肿,或者是抗癫痫药物水平迅速的变化。
Objective To explore the effect of levetiracetam ( LEV), a new type antiepileptic drug, as an addon therapy on acute postoperative seizures ( APOS) in adults with refractory temporal epilepsy. 目的观察新型抗疒间药物左乙拉西坦(LEV)联合治疗对成人颞叶癫疒间术后早发性癫疒间(APOS)的预防作用。
Objective To prevent the risk of exacerbation or status epileptics occurred following withdrawal of antiepileptic drug ( AEDs), shorten mean hospitalization and reduce expenses. 目的缩短平均住院日,降低医疗费用,防止抗癫痫药撤换时所致的癫痫持续状态。
Monitoring of antiepileptic drug serum concentrations and the clinical significance in 223 children 223例小儿抗癫癎药物血药浓度监测及其临床意义
Objective To study the toxicity of topiramate ( TPM), an antiepileptic drug, on embryonic development in rats. 目的研究妥泰(topiramate,TPM)对大鼠胚胎发育的毒性。
Effect of Antiepileptic Drug on Bone Mineral Density in Adult Epileptic Patients 抗癫痫药对成人骨密度的影响
Objective: To study the effect of antiepileptic drug phenobarbital Phenobar ( P.B.) 目的:探讨抗癫痫药***对癫痫患儿甲状腺功能的影响。
Antiepileptic Drug Use and Birth Rate in Patients with Epilepsy& a Population-based Cohort Study in Finland 在癫痫患者中抗癫痫药物的使用以及出生率&一项在芬兰的队列研究
Oxcarbazepine is a new antiepileptic drug that has been approved for the treatment of partial onset seizures and generalized tonic-clonic seizures. 奥卡西平是一种治疗癫痫部分发作和全身强直阵挛性癫痫发作的新药。
Immediate versus deferred antiepileptic drug treatment for early epilepsy and single seizures: A randomised controlled trial 一项即刻与推迟应用抗癫痫药治疗早期癫痫与单次癫痫发作的随机对照试验
Clinical and pathological analysis in one case of antiepileptic drug hypersensitivity syndrome 抗癫痫药高敏综合征临床及病理分析
Effect of antiepileptic drug comedication on lamotrigine clearance 抗癫痫药物联合应用对拉莫三嗪清除率的影响
Objective: To discuss the clinical features, diagnosis, pathogenesis and treatment of antiepileptic drug hypersensitivity syndrome ( AHS). 目的:探讨抗癫痫药高敏综合征(AHS)的临床特点、诊断、发病机理及治疗。
Frequently used prophylactic treatment medicines included calcium antagonist, tricyclic antidepressant ( TCA),β-receptor blocking pharmacon and antiepileptic drug ( AED) and so on. 常用的预防性治疗药物包括钙拮抗剂、三环类抗抑郁药、β-受体阻断剂和抗癫痫药等。
Third, our findings suggest that GABA transporter tiagabine may have cognitive side effect as a clinical used antiepileptic drug. 第三,我们发现GABA转运体的抑制剂噻加宾作为临床药物可能具有认知损伤的副作用。
Patients were divided into different antiepileptic drug groups. 根据患者用药的不同将其分成不同的抗癫痫药物组。
Tiagabine is a GABA transporter inhibitor and has already been used as a clinical antiepileptic drug. 噻加宾就是这样一个已经用于临床的GABA转运体阻断剂。
Although anti-epileptic drugs continuous research and development, but for refractory epilepsy, the new antiepileptic drug treatment appears to be limited. There is need to find other means and methods of treatment. 虽然抗癫痫药不断研发,但对于难治性癫痫,新型抗癫痫药治疗的疗效仍然有限,需要寻找其它的治疗手段和方法。
Because of its significant efficacy, carbamazepine is often used as a drug for the treatment of epilepsy and neuropathic pain, and is classified as a first-line antiepileptic drug. 抗癫痫药卡马西平由于药效显著,常作为治疗癫痫和神经痛的首选药物被大量使用。卡马西平是目前广泛应用的一线抗癫痫药。